AAWSAP DIRD, Biomaterials, January 2010
DOW-UAP-D119 · page 5 of 32
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UNCLASSIFIED/ /POR. orr1e1J1tt tl.!I!!! OHLY Biomaterials Introduction Biomaterials are metals, ceramics, polymers, glasses, carbons, and composite materials intended to interface with biological systems. They are often used to treat, augment, or replace bodily tissues, organs, or functions. Such materials are used in various forms, including molded or machined parts, coatings, fibers, films, foams, and fabrics. Biomaterials are usually nonliving, but recent definitions also include living skin and tissues produced in culture. A biocompatible material is different from a biological material produced by a biological system, such as bone. Artificial hips, vascular stents, artificial pacemakers, and catheters are all made of biocompatible materials that typically have a synthetic origin. An extraordinarily wide range of medical devices are made from biomaterials. Figure 1 shows some representative examples of medical devices that use biomaterials. Finger joint Breast implant Heart valve .lloooe rubber Hip j int tifi ial heart poly\lr Figure 1. Biomaterial Applications in Medical Devices Encompassing elements of medicine, biology, chemistry, and materials science, biomaterials science has experienced steady and strong growth over its approximately half-century history. Although biomaterials are used primarily for medical applications, they are also used to grow cells in culture, to assay for blood proteins in the clinical UNCLASSIFIED//FOR OFFICIAL USE ONLY vi