John Company

AAWSAP DIRD, Technological Approaches to Controlling External Devices, March 2010

DOW-UAP-D130 · page 3 of 36

Page 3 of 36 of DOW-UAP-D130

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Contents
Introduction ............................................................................................................v
Direct Neural Signals.............................................................................................. 1
Indirect Neuronal Signals - The BOLD Effect.......................................................... 3
Control of External Devices .................................................................................... 4
Noninvasive Technologies ...................................................................................... 6
EEG ..................................................................................................................... 7
MEG .................................................................................................................... 8
EMG .................................................................................................................... 9
MRI and fMRI ..................................................................................................... 9
NIRS.................................................................................................................... 10
Invasive Technologies.......................................................................................... 10
Open-Loop Direct Cortical Array Algorithm Modeling ....................................... 11
Closed-Loop Peripheral Arrays Utilizing Visual Feedback ................................. 13
MEMS, ECoG, and PSoC Circuitry ...................................................................... 14
Chronic Neural Implants and fMRI ................................................................... 16
New Electrode Designs..................................................................................... 18
Hybrid Neuro-Robotic Systems for True Closed-Loop BMI ................................ 20
Trials Using Human Subjects............................................................................ 22
Optical Stimulation of Action Potentials ........................................................... 23
Discussion ............................................................................................................ 23
Noninvasive Electrical Devices ......................................................................... 24
Noninvasive BOLD-Based devices..................................................................... 25
Noninvasive Magnetic Devices ......................................................................... 26
Invasive Technologies - General, Optical, and Ex-Vivo Engineering................. 26
Implantable Chips, Ladders, and Arrays ........................................................... 27
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