John Company

AAWSAP DIRD, Quantum Computing and Utilizing Organic Molecules in Automation Technology, December 2010

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substrates and size of legs are adjusted well, the assembly is continuously moving to new
substrate-covered areas. Due to residual binding of deoxyribozymes to products, even if the
spiders were surrounded by the product-covered areas, they would be able to move over
them by ordinary random walk, until they would find substrates again. Importantly,
directional movement of spiders can be accomplished by aligning substrates in directional
paths, for example, by displaying them on self-assembled structures, including origami
(Figure 27). Further, simple computing can be introduced by logic gates as legs. The nano
walker could be hybridized to repair DNA based machinery, including DNA computers, when
they are being assembled, or when they are damaged from cosmic rays, for example.
Figure 26. The Nano walker made at Columbia University is a
protein molecule decorated with three legs--single-stranded
DNAzymes, synthetic DNA molecules that act as enzymes and
catalyze a reaction.
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